Michael Halassa, Guoping Feng, and colleagues show that a genetic deficit found in patients with ADHD produces (in mice) deficit in the thalamic reticular nucleus. This adds to Halassa’s recent work (also in Nature) suggesting that attention is focused when the prefrontal cortex acts on sensory cortex via the thalamus. It adds a link to potential path to treatment. Cool.
Thalamic reticular impairment underlies attention deficit in Ptchd1Y/− mice
Michael F. Wells, Ralf D. Wimmer, L. Ian Schmitt, Guoping Feng & Michael M. Halassa
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Miller Lab
The Miller Lab uses experimental and theoretical approaches to study the neural basis of the high-level cognitive functions that underlie complex goal-directed behavior. ekmillerlab.mit.edu