Wutz, A., Loonis, R., Roy, J.E., Donoghue, J.A., and Miller, E.K. (2018) Different levels of category abstraction by different dynamics in different prefrontal areas. Neuron published online Jan 25 2018.
Categories can be grouped by shared sensory attributes (i.e. cats) or by a more abstract rule (i.e. animals). We explored the neural basis of abstraction by recording from multi-electrode arrays in prefrontal cortex (PFC) while monkeys performed a dot-pattern categorization task. Category abstraction was varied by the degree of exemplar distortion from the prototype pattern. Different dynamics in different PFC regions processed different levels of category abstraction. Bottom-up dynamics (stimulus-locked gamma power and spiking) in ventral PFC processed more low-level abstractions whereas top-down dynamics (beta power and beta spike-LFP coherence) in dorsal PFC processed more high-level abstractions. Our results suggest a two-stage, rhythm-based model for abstracting categories.
About the Author
The Miller Lab uses experimental and theoretical approaches to study the neural basis of the high-level cognitive functions that underlie complex goal-directed behavior. ekmillerlab.mit.edu