An excellent, comprehensive review of the neurobiology of decision-making by David Freedman and John Asaad.
Neuronal Mechanisms of Visual Categorization: An Abstract View on Decision Making
David J. Freedman and John A. Assad, Annual Review of Neuroscience, 2016
This study shows the role of alpha and beta oscillations in the prefrontal cortex and frontal eye fields in a classic test of cognitive control: anti-saccades. It also shows how these oscillatory patterns develop with adulthood.
Hwang, Kai, et al. “Frontal preparatory neural oscillations associated with cognitive control: A developmental study comparing young adults and adolescents.” NeuroImage (2016).
Miller Lab Alumnus Andreas Nieder tells you everything you need to know about the brain substrates of the sense of number:
Nieder, Andreas. “The neuronal code for number.” Nature Reviews Neuroscience (2016).
Nice review of past work on the neurobiology of working memory and capacity limits:
Constantinidis, Christos, and Torkel Klingberg. “The neuroscience of working memory capacity and training.” Nature Reviews Neuroscience (2016).
Although there is a caveat: More recent work suggests that the substrate of working memory is *not* sustained spiking activity. That is an artifact of cross-trial averaging. “Delay activity” is more sparse and bursty on single trials. This suggests a different memory substrate.
Lunqvist, M., Rose, J., Herman, P, Brincat, S.L, Buschman, T.J., and Miller, E.K. (2016) Gamma and beta bursts underlie working memory. Neuron, published online March 17, 2016. View PDF
Stokes, Mark G. “‘Activity-silent’working memory in prefrontal cortex: a dynamic coding framework.” Trends in cognitive sciences 19.7 (2015): 394-405.
Stokes and Spaak review our recent work on single-trial analysis of working memory “delay” activity. This showed that the classic profile of sustained activity as the memory substrate is an artifact of averaging across trials. The assumption is that averaging cancels out noise. Instead, it may be covering up important details of the dynamics of neural activity.
Read more here:
The Importance of Single-Trial Analyses in Cognitive Neuroscience
Mark Stokes and Eelke Spaak
Trends in Cognitive Sciences
The original paper:
Lunqvist, M., Rose, J., Herman, P, Brincat, S.L, Buschman, T.J., and Miller, E.K. (2016) Gamma and beta bursts underlie working memory. Neuron, published online March 17, 2016. View PDF »
A wonderful tribute to a dear friend
Nice paper showing that different task demands in different task stages engage different oscillatory bands in the prefrontal cortex.
Wimmer, Klaus, et al. “Transitions between Multiband Oscillatory Patterns Characterize Memory-Guided Perceptual Decisions in Prefrontal Circuits.”The Journal of Neuroscience 36.2 (2016): 489-505.
That is all
Despite Bans, Many Still Text While Driving. Radio Boston WBUR 90.0 FM
Earl Miller receives the Kent State University Professional Achievement Award from KSU President Beverly Warren.
And delivers the Commencement Address: