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  • In the News
  • 28
    Oct 2014

    New review: Goal-direction and top-down control


    Miller Lab
    Miller Laboratory, Neuroscience

    Goal-direction and top-down control
    Timothy J. Buschman and Earl K. Miller

    We review the neural mechanisms that support top-down control of behavior.  We suggest that goal-directed behavior utilizes two systems that work in concert.  A basal ganglia-centered system quickly learns simple, fixed goal-directed behaviors while a prefrontal cortex-centered system gradually learns more complex (abstract or long-term) goal-directed behaviors.  Interactions between these two systems allows top-down control mechanisms to learn how to direct behavior towards a goal but also how to guide behavior when faced with a novel situation.

    Read it here

  • 6
    Oct 2014

    Tim Buschman is a winner of NIH New Innovator Award


    Miller Lab
    In The News, Miller Laboratory

    Miller Lab Alumnus Tim Buschman is one of the winners of the NIH Director’s New Innovator Award.

    According to the NIH website: The award “is designed specifically to support unusually creative new investigators with highly innovative research ideas at an early stage of their career when they may lack the preliminary data required for an R01 grant.”

    We couldn’t be prouder of him if we were a Little Lebowski Urban Achiever.

  • 26
    Sep 2014

    Tweeting While Watching TV Linked to Fewer Brain Cells


    Miller Lab
    In The News, Miller Laboratory

    “Linked” is the operative term here.  Earl Miller is quoted in a New York Magazine article about a study that finds less gray matter in people who multitask more.  Earl points out that the study does not necessarily mean that multitasking decreases brain matter.  It could be that people with less gray matter are more impulsive and thus more prone to multitasking.

    Tweeting While Watching TV Linked to Fewer Brain Cells

  • 11
    Sep 2014

    Functional Specialization in the Human Brain Estimated By Intrinsic Hemispheric Interaction


    Miller Lab
    Miller Laboratory, Neuroscience

    At this risk of kvelling, in 2011 we published a paper (Buschman et al., 2011) showing independent visual working memory capacities in the right vs left visual hemifields.  We were told “no way” and “that’s impossible”.  Since then, a bunch of papers have supported this.  Here’s another one.

    Wang et al used FMRI and found that brain networks primarily interact with ipsilateral, not contralateral networks.  Thus, the brain emphasizes processing within each hemisphere (visual hemifield) and minimizes across-hemisphere processing.

    Also see:
    Buschman,T.J., Siegel, M., Roy, J.E. and Miller, E.K. (2011) Neural substrates of cognitive capacity limitations. Proceedings of the National Academy of Sciences. 108(27):11252-5. View PDF »

  • 14
    Jun 2014

    We make IFLScience: Brain Waves Synchronize for Faster Learning


    Miller Lab
    Miller Laboratory, Neuroscience

    IFLScience: Brain Waves Synchronize for Faster Learning

    Summary:
    As our thoughts dart from this to that, our brains absorb and analyze new information at a rapid pace. According to a new study, these quickly changing brain states may be encoded by the synchronization of brain waves across different brain regions. Waves originating from two areas involved in learning couple to form new communication circuits when monkeys learn to categorize different patterns of dots.

    Read more here

  • 13
    Jun 2014

    Synchronous brain waves study on the radio


    Miller Lab
    Miller Laboratory, Neuroscience

    A (very brief) mention of the new paper by Antzoulatos and Miller (2014) on National Public Radio.

    The paper:
    Antzoulatos, E.G. and Miller, E.K. (in press)  “Increases in functional connectivity between the prefrontal cortex and striatum during category learning.”  Neuron. View PDF

  • 13
    Jun 2014

    You’re Not Busy, You Just Think You Are: 7 Ways To Find More Time


    Miller Lab
    Miller Laboratory, Neuroscience, Psychology

    Huffington Post article about the evils of multitasking.
    You’re Not Busy, You Just Think You Are: 7 Ways To Find More Time  The Huffington Post UK | By Georgia James Posted: 13/06/2014 15:00 BST
    (with quotes from Earl Miller)

  • 12
    Jun 2014

    Synchronized brain waves enable rapid learning


    Miller Lab
    Miller Laboratory, Neuroscience

    Antzoulatos EG and Miller EK  (in press) Increases in Functional Connectivity between Prefrontal Cortex and Striatum during Category Learning. Neuron, in press.
    DOI: http://dx.doi.org/10.1016/j.neuron.2014.05.005

    Animals were trained to learn new category groupings by trial and error.  Once they started to “get” the categories, there was an increase in beta-band synchrony between the prefrontal cortex and striatum, two brain areas critical for learning.  By the time the categories were well-learned, the beta synchrony between the areas became category-specific, that is, unique sets of sites in the prefrontal cortex and striatum showed increased beta synchrony for the two different categories.  This suggests that synchronization of brain rhythms can quickly establish new functional brain circuits and thus support cognitive flexibility, a hallmark of intelligence.

    MIT Press release:
    Synchronized brain waves enable rapid learning
    MIT study finds neurons that hum together encode new information.

  • 11
    Jun 2014

    Neuronal Correlates of Visual Working Memory in the Corvid Endbrain


    Miller Lab
    Miller Laboratory, Neuroscience

    A well-known correlate of working memory is sustained neural activity that bridges short gaps in time.  It is well-established in the primate brain, but what about birds?  They have working memory.  (In fact, there is a lot of classic work that detailed the behavioral characteristics of working memory in pigeons).

    Miller Lab alumnus Andreas Nieder and crew trained crows to perform a working memory task and found sustained activity in the nidopallium caudolaterale (NCL).  This is presumably a neural correlate of the crow’s visual working memory.

    Now if crows could only pass that causality test.

  • 18
    Apr 2014

    Videos: Rhythmic Dynamics and Cognition 6-4-13


    Miller Lab
    Miller Laboratory, Neuroscience

    See lectures from the Cognitive Rhythms Collaborative conference on Rhythmic Dynamics and Cognition, which took place on June 4, 2013 at MIT.

    Talks:
    Elizabeth Buffalo: Neural Signals for Memory and Space in the Primate Medial Temporal Lobe
    Earl K. Miller: Cognition is Rhythmic
    Robert Knight: Oscillations and Human PFC
    Peter Ulhaas: Neural Oscillations in Schizophrenia: Perspectives from MEG
    Charles Schroeder: Neural Substrates of Temporal Prediction in Active Sensing
    Peter Brown: Beta Oscillations in the Human Basal Ganglia
    Christa van Dort: Optogenetic Activation of Cholinergic Neurons in the PPT Induces REM Sleep
    Rosalyn Doran: Dynamic Causal Modeling and Neurophysiology
    Liam Paninski: Statistical Neuroscience
    Astrid Prinz: How do rhythmically active circuits “analyze” their own activity?

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