Roux and Uhlhaas propose an interesting and provocative theory: Different frequencies of neural oscillations carry different information in working memory.  Gamma oscillations maintain information in working memory.  Alpha suppresses irrelevant information.  Theta orders information.  Gamma is thought to be coupled to both alpha and theta.

This is consistent with our observations for phase-coding of different working memories in gamma (Siegel et al., 2009) and alpha suppressing a dominant, but current irrelevant, neural ensemble (Buschman et al., 2012).

Buschman, T.J., Denovellis, E.L., Diogo, C., Bullock, D. and Miller, E.K. (2012) Synchronous oscillatory neural ensembles for rules in the prefrontal cortex.  Neuron. 76: 838-846. View PDF »

Siegel, M., Warden, M.R., and Miller, E.K. (2009) Phase-dependent neuronal coding of objects in short-term memory. Proceedings of the National Academy of Sciences, 106: 21341-21346. View PDF »

About the Author

The Miller Lab uses experimental and theoretical approaches to study the neural basis of the high-level cognitive functions that underlie complex goal-directed behavior.