The modal model of working memory (WM) is that of sustained activity in the prefrontal cortex.  Sreenivasan et al argue for a more complex model.  High-fidelity WM representations are maintained in sensory cortex while the prefrontal cortex instead maintains representations of multiple goal-related variables.  These PFC representations serve to bias stimulus-specific activity in sensory cortex.

About the Author

The Miller Lab uses experimental and theoretical approaches to study the neural basis of the high-level cognitive functions that underlie complex goal-directed behavior.