Pinto and Dan use Ca2+ imaging to identify different subtypes of inhibitory neurons in the mouse prefrontal cortex.  They found that different subtypes encode different aspects of the task. By contrast, excitatory neurons are diverse and their task-related activity by cortical layer.

Pinto, Lucas, and Yang Dan. “Cell-Type-Specific Activity in Prefrontal Cortex during Goal-Directed Behavior.” Neuron (2015).

About the Author

The Miller Lab uses experimental and theoretical approaches to study the neural basis of the high-level cognitive functions that underlie complex goal-directed behavior.