Driscoll et al tracked parietal cortex neurons over one month after mice learned and practiced a navigation task. The activity of individual neurons changed but information on the population level was stable. This is a nice demonstration of “mixed selectivity” in individual neurons and further evidence that the functional unit of the brain is neural ensembles, not individual neurons.
Driscoll, L. N., Pettit, N. L., Minderer, M., Chettih, S. N., & Harvey, C. D. (2017). Dynamic reorganization of neuronal activity patterns in parietal cortex. Cell.
For further reading:
Fusi, S., Miller, E.K., and Rigotti, M. (2016) Why neurons mix: High dimensionality for higher cognition. Current Opinion in Neurobiology. 37:66-74 doi:10.1016/j.conb.2016.01.010. View PDF »
Rigotti, M., Barak, O., Warden, M.R., Wang, X., Daw, N.D., Miller, E.K., & Fusi, S. (2013) The importance of mixed selectivity in complex cognitive tasks. Nature, 497, 585-590, doi:10.1038/nature12160. View PDF »
About the Author
The Miller Lab uses experimental and theoretical approaches to study the neural basis of the high-level cognitive functions that underlie complex goal-directed behavior. ekmillerlab.mit.edu